Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure

BACKGROUND: Drug-induced liver injury (DILI) is a major safety concern characterized by a complex and diverse pathogenesis. In order to identify DILI early in drug development, a better understanding of the injury and models with better predictivity are urgently needed. One approach in this regard a...

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Detalles Bibliográficos
Autores principales: Liu, Anika, Walter, Moritz, Wright, Peter, Bartosik, Aleksandra, Dolciami, Daniela, Elbasir, Abdurrahman, Yang, Hongbin, Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814730/
https://www.ncbi.nlm.nih.gov/pubmed/33461600
http://dx.doi.org/10.1186/s13062-020-00285-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814730/
https://www.ncbi.nlm.nih.gov/pubmed/33461600
http://dx.doi.org/10.1186/s13062-020-00285-0

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