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Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits

BACKGROUND: Disruptions of brain-gut axis have been implicated in the progression of a variety of gastrointestinal (GI) disorders and central nervous system (CNS) diseases and injuries, including traumatic brain injury (TBI). TBI is a chronic disease process characterized by persistent secondary inj...

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Detalles Bibliográficos
Autores principales: Hanscom, Marie, Loane, David J., Aubretch, Taryn, Leser, Jenna, Molesworth, Kara, Hedgekar, Nivedita, Ritzel, Rodney M., Abulwerdi, Gelareh, Shea-Donohue, Terez, Faden, Alan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814749/
https://www.ncbi.nlm.nih.gov/pubmed/33461596
http://dx.doi.org/10.1186/s12974-020-02067-x