Evaluation of Microwave Vacuum Drying as an Alternative to Freeze-Drying of Biologics and Vaccines: the Power of Simple Modeling to Identify a Mechanism for Faster Drying Times Achieved with Microwave

Vial-based lyophilization for biopharmaceuticals has been an indispensable cornerstone process for over 50 years. However, the process is not without significant challenges. Capital costs to realize a lyophilized drug product facility, for example, are very high. Similarly, heat and mass transfer li...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhambhani, Akhilesh, Stanbro, Justin, Roth, Daniel, Sullivan, Elizabeth, Jones, Morrisa, Evans, Robert, Blue, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814865/
https://www.ncbi.nlm.nih.gov/pubmed/33469785
http://dx.doi.org/10.1208/s12249-020-01912-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814865/
https://www.ncbi.nlm.nih.gov/pubmed/33469785
http://dx.doi.org/10.1208/s12249-020-01912-9

Ejemplares similares