The Early Evolution of Oral Poliovirus Vaccine Is Shaped by Strong Positive Selection and Tight Transmission Bottlenecks

The emergence of circulating vaccine-derived polioviruses through evolution of the oral polio vaccine (OPV) poses a significant obstacle to polio eradication. Understanding the early genetic changes that occur as OPV evolves and transmits is important for preventing future outbreaks. Here, we use de...

Descripción completa

Detalles Bibliográficos
Autores principales: Valesano, Andrew L., Taniuchi, Mami, Fitzsimmons, William J., Islam, Md Ohedul, Ahmed, Tahmina, Zaman, Khalequ, Haque, Rashidul, Wong, Wesley, Famulare, Michael, Lauring, Adam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815045/
https://www.ncbi.nlm.nih.gov/pubmed/33212020
http://dx.doi.org/10.1016/j.chom.2020.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815045/
https://www.ncbi.nlm.nih.gov/pubmed/33212020
http://dx.doi.org/10.1016/j.chom.2020.10.011

Ejemplares similares