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miR-129-3p Targeting of MCU Protects Against Glucose Fluctuation-Mediated Neuronal Damage via a Mitochondrial-Dependent Intrinsic Apoptotic Pathway

INTRODUCTION: Glucose fluctuations have an adverse effect on several diabetes-related complications, especially for the nervous system, but the underlying mechanisms are not clear. MicroRNAs are critical regulators of posttranscription in many physiological processes, such as apoptosis. Our study cl...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Yang, You, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815084/
https://www.ncbi.nlm.nih.gov/pubmed/33488104
http://dx.doi.org/10.2147/DMSO.S285179