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Echogenic, Ultrasound-Sensitive Chitosan Nanodroplets for Spatiotemporally Controlled DKK-2 Gene Delivery to Prostate Cancer Cells

PURPOSE: To synthesize echogenic chitosan/perfluorohexane nanodroplets (CNDs) for DKK-2 gene delivering in a spatiotemporally controlled manner in vitro. METHODS: The characteristics, contrast-enhanced ultrasound imaging, DNA binding and DNase protection capacity, DKK-2 gene transfection and effects...

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Detalles Bibliográficos
Autores principales: Liu, Xinxin, Shi, Dandan, Guo, Lu, Zhou, Xiaoying, Shang, Mengmeng, Sun, Xiao, Meng, Dong, Zhao, Yading, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815087/
https://www.ncbi.nlm.nih.gov/pubmed/33488078
http://dx.doi.org/10.2147/IJN.S286474