Blocking IL-10 signaling with soluble IL-10 receptor restores in vitro specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum

rIL-10 plays a major role in restricting exaggerated inflammatory and immune responses, thus preventing tissue damage. However, the restriction of inflammatory and immune responses by IL-10 can also favor the development and/or persistence of chronic infections or neoplasms. Dogs that succumb to can...

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Detalles Bibliográficos
Autores principales: Santos, Catiule de Oliveira, Costa, Sidnei Ferro, Souza, Fabiana Santana, Mendes, Jessica Mariane Ferreira, de Pinheiro, Cristiane Garboggini Melo, Moreira, Diogo Rodrigo de Magalhães, Silva, Luciano Kalabric, de Lima, Valeria Marçal Felix, de Sá Oliveira, Geraldo Gileno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815104/
https://www.ncbi.nlm.nih.gov/pubmed/33465107
http://dx.doi.org/10.1371/journal.pone.0239171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815104/
https://www.ncbi.nlm.nih.gov/pubmed/33465107
http://dx.doi.org/10.1371/journal.pone.0239171

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