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Myogenin is required for assembly of the transcription machinery on muscle genes during skeletal muscle differentiation

Skeletal muscle gene expression is governed by the myogenic regulatory family (MRF) which includes MyoD (MYOD1) and myogenin (MYOG). MYOD1 and MYOG are known to regulate an overlapping set of muscle genes, but MYOD1 cannot compensate for the absence of MYOG in vivo. In vitro, late muscle genes have...

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Detalles Bibliográficos
Autores principales: Adhikari, Abhinav, Kim, William, Davie, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815108/
https://www.ncbi.nlm.nih.gov/pubmed/33465133
http://dx.doi.org/10.1371/journal.pone.0245618