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Hsa_circ_0006571 promotes spinal metastasis through sponging microRNA-138 to regulate sirtuin 1 expression in lung adenocarcinoma

BACKGROUND: Circular RNAs (circRNAs) are known to participate in lung cancer. However, their role in spinal metastasis (SM) of lung adenocarcinoma remains elusive. In this study, we determined that hsa_circ_0006571 serves as a sponge for miR-138, which targets sirtuin 1 (Sirt1) in the development of...

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Detalles Bibliográficos
Autores principales: Wang, Hou-Lei, Wang, Hui-Ren, Liang, Yun, Hu, An-Nan, Enguita, Francisco J., Zhou, Xiao-Gang, Dong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815347/
https://www.ncbi.nlm.nih.gov/pubmed/33489803
http://dx.doi.org/10.21037/tlcr-20-1250