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A case report of exceptional clinical response to chemoradiotherapy and tyrosine kinase inhibitors in a patient with EML4-ALK fusion variant 1 non-small cell lung cancer

Echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion occurs in approximately 5% of non-small cell lung cancer (NSCLC) cases. Variants 1 and 3a/b are the most common EML4-ALK variants. Emerging evidence indicates that patients with variant 1 and those with v...

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Detalles Bibliográficos
Autores principales: Xu, Xinyan, Liu, Di, Wen, Junmiao, Chen, Jiayan, Fan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815360/
https://www.ncbi.nlm.nih.gov/pubmed/33489810
http://dx.doi.org/10.21037/tlcr-20-1212