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Coexistence of a novel CCNY-ALK and ATIC-ALK double-fusion in one patient with ALK-positive NSCLC and response to crizotinib: a case report

Anaplastic lymphoma kinase (ALK) rearrangement, one of the common oncogene rearrangements in the mutational history of lung adenocarcinoma, occurs in approximately 5% of non-small cell lung cancer (NSCLC) patients who could be effectively treated with ALK tyrosine kinase inhibitors (TKIs). The earli...

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Detalles Bibliográficos
Autores principales: Wu, Xuan, Zhou, Hanqiong, He, Zhen, Zhang, Zhe, Feng, Wen, Zhao, Jiuzhou, Chen, Haiyang, Wang, Shuai, Wang, Wei, Wang, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815378/
https://www.ncbi.nlm.nih.gov/pubmed/33489809
http://dx.doi.org/10.21037/tlcr-20-1049