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Rheumatoid arthritis CD14(+) monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease

INTRODUCTION: This study investigates the metabolic activity of circulating monocytes and their impact on pro‐inflammatory responses in RA and explores whether this phenotype is already primed for inflammation before clinical manifestations of disease. METHODS: Blood was collected and CD14(+) monocy...

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Detalles Bibliográficos
Autores principales: McGarry, Trudy, Hanlon, Megan M., Marzaioli, Viviana, Cunningham, Clare C, Krishna, Vinod, Murray, Kieran, Hurson, Conor, Gallagher, Phil, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815439/
https://www.ncbi.nlm.nih.gov/pubmed/33510894
http://dx.doi.org/10.1002/cti2.1237