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Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation

OBJECTIVE: Systemic inflammation predisposes acutely decompensated (AD) cirrhosis to the development of acute-on-chronic liver failure (ACLF). Supportive treatment can improve AD patients, becoming recompensated. Little is known about the outcome of patients recompensated after AD. We hypothesise th...

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Detalles Bibliográficos
Autores principales: Monteiro, Sofia, Grandt, Josephine, Uschner, Frank Erhard, Kimer, Nina, Madsen, Jan Lysgård, Schierwagen, Robert, Klein, Sabine, Welsch, Christoph, Schäfer, Liliana, Jansen, Christian, Claria, Joan, Alcaraz-Quiles, José, Arroyo, Vicente, Moreau, Richard, Fernandez, Javier, Bendtsen, Flemming, Mehta, Gautam, Gluud, Lise Lotte, Møller, Søren, Praktiknjo, Michael, Trebicka, Jonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815638/
https://www.ncbi.nlm.nih.gov/pubmed/32241903
http://dx.doi.org/10.1136/gutjnl-2019-320170