Mathematical modeling of depressive disorders: Circadian driving, bistability and dynamical transitions

The hypothalamus–pituitary–adrenal (HPA) axis is a key neuroendocrine system implicated in stress response, major depression disorder, and post-traumatic stress disorder. We present a new, compact dynamical systems model for the response of the HPA axis to external stimuli, representing stressors or...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoou, D’Orsogna, Maria R., Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815682/
https://www.ncbi.nlm.nih.gov/pubmed/33510869
http://dx.doi.org/10.1016/j.csbj.2020.10.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815682/
https://www.ncbi.nlm.nih.gov/pubmed/33510869
http://dx.doi.org/10.1016/j.csbj.2020.10.035

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