Cargando…
Mathematical modeling of depressive disorders: Circadian driving, bistability and dynamical transitions
The hypothalamus–pituitary–adrenal (HPA) axis is a key neuroendocrine system implicated in stress response, major depression disorder, and post-traumatic stress disorder. We present a new, compact dynamical systems model for the response of the HPA axis to external stimuli, representing stressors or...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815682/ https://www.ncbi.nlm.nih.gov/pubmed/33510869 http://dx.doi.org/10.1016/j.csbj.2020.10.035 |