Adipokine Leptin Co-operates With Mechanosensitive Ca(2 +)-Channels and Triggers Actomyosin-Mediated Motility of Breast Epithelial Cells
In postmenopausal women, a major risk factor for the development of breast cancer is obesity. In particular, the adipose tissue-derived adipokine leptin has been strongly linked to tumor cell proliferation, migration, and metastasis, but the underlying mechanisms remain unclear. Here we show that tr...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815691/ https://www.ncbi.nlm.nih.gov/pubmed/33490070 http://dx.doi.org/10.3389/fcell.2020.607038 |