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Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53
It has been postulated that cancer stem cells (CSCs) are involved in all aspects of human cancer, although the mechanisms governing the regulation of CSC self-renewal in the cancer state remain poorly defined. In the literature, both the pro- and anti-oncogenic activities of autophagy have been demo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815724/ https://www.ncbi.nlm.nih.gov/pubmed/33468994 http://dx.doi.org/10.1038/s41419-021-03392-6 |