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Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53

It has been postulated that cancer stem cells (CSCs) are involved in all aspects of human cancer, although the mechanisms governing the regulation of CSC self-renewal in the cancer state remain poorly defined. In the literature, both the pro- and anti-oncogenic activities of autophagy have been demo...

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Detalles Bibliográficos
Autores principales: Wang, Jianyu, Liu, Doudou, Sun, Zhiwei, Ye, Ting, Li, Jingyuan, Zeng, Bin, Zhao, Qiting, Rosie Xing, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815724/
https://www.ncbi.nlm.nih.gov/pubmed/33468994
http://dx.doi.org/10.1038/s41419-021-03392-6

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