Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

Conventional dendritic cells (cDC) are key activators of naive T cells, and can be targeted in adults to induce adaptive immunity, but in early life are considered under-developed or functionally immature. Here we show that, in early life, when the immune system develops, cDC2 exhibit a dual hematop...

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Detalles Bibliográficos
Autores principales: Papaioannou, Nikos E., Salei, Natallia, Rambichler, Stephan, Ravi, Kaushikk, Popovic, Jelena, Küntzel, Vanessa, Lehmann, Christian H. K., Fiancette, Remi, Salvermoser, Johanna, Gajdasik, Dominika W., Mettler, Ramona, Messerer, Denise, Carrelha, Joana, Ohnmacht, Caspar, Haller, Dirk, Stumm, Ralf, Straub, Tobias, Jacobsen, Sten Eirik W., Schulz, Christian, Withers, David R., Schotta, Gunnar, Dudziak, Diana, Schraml, Barbara U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815729/
https://www.ncbi.nlm.nih.gov/pubmed/33469015
http://dx.doi.org/10.1038/s41467-020-20659-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815729/
https://www.ncbi.nlm.nih.gov/pubmed/33469015
http://dx.doi.org/10.1038/s41467-020-20659-2

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