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LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes

Leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins have been implicated as regulators of growth factor signaling; however, the possible redundancy among mammalian LRIG1, LRIG2, and LRIG3 has hindered detailed elucidation of their physiological functions. Here, we show that Lrig-nul...

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Detalles Bibliográficos
Autores principales: Herdenberg, Carl, Mutie, Pascal M., Billing, Ola, Abdullah, Ahmad, Strawbridge, Rona J., Dahlman, Ingrid, Tuck, Simon, Holmlund, Camilla, Arner, Peter, Henriksson, Roger, Franks, Paul W., Hedman, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815736/
https://www.ncbi.nlm.nih.gov/pubmed/33469151
http://dx.doi.org/10.1038/s42003-020-01613-w