Molecular basis of IRGB10 oligomerization and membrane association for pathogen membrane disruption

Immunity-related GTPase B10 (IRGB10) belongs to the interferon (IFN)-inducible GTPases, a family of proteins critical to host defense. It is induced by IFNs after pathogen infection, and plays a role in liberating pathogenic ligands for the activation of the inflammasome by directly disrupting the p...

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Detalles Bibliográficos
Autores principales: Ha, Hyun Ji, Chun, Hye Lin, Lee, So Yeon, Jeong, Jae-Hee, Kim, Yeon-Gil, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815755/
https://www.ncbi.nlm.nih.gov/pubmed/33469160
http://dx.doi.org/10.1038/s42003-020-01640-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815755/
https://www.ncbi.nlm.nih.gov/pubmed/33469160
http://dx.doi.org/10.1038/s42003-020-01640-7

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