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Molecular basis of IRGB10 oligomerization and membrane association for pathogen membrane disruption
Immunity-related GTPase B10 (IRGB10) belongs to the interferon (IFN)-inducible GTPases, a family of proteins critical to host defense. It is induced by IFNs after pathogen infection, and plays a role in liberating pathogenic ligands for the activation of the inflammasome by directly disrupting the p...
Autores principales: | Ha, Hyun Ji, Chun, Hye Lin, Lee, So Yeon, Jeong, Jae-Hee, Kim, Yeon-Gil, Park, Hyun Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815755/ https://www.ncbi.nlm.nih.gov/pubmed/33469160 http://dx.doi.org/10.1038/s42003-020-01640-7 |
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