Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2

WHSC1 is a histone methyltransferase that facilitates histone H3 lysine 36 dimethylation (H3K36me2), which is a permissive mark associated with active transcription. In this study, we revealed how WHSC1 regulates tumorigenesis and chemosensitivity of colorectal cancer (CRC). Our data showed that WHS...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Zhu, Liming, Guo, Mei, Sun, Gang, Zhou, Kun, Pang, Wenjing, Cao, Dachun, Tang, Xin, Meng, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815777/
https://www.ncbi.nlm.nih.gov/pubmed/33469000
http://dx.doi.org/10.1038/s41420-021-00402-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815777/
https://www.ncbi.nlm.nih.gov/pubmed/33469000
http://dx.doi.org/10.1038/s41420-021-00402-6

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