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Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

Legionella pneumophila infects eukaryotic cells by forming a replicative organelle – the Legionella containing vacuole. During this process, the bacterial protein DrrA/SidM is secreted and manipulates the activity and post-translational modification (PTM) states of the vesicular trafficking regulato...

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Detalles Bibliográficos
Autores principales: Du, Jiqing, Wrisberg, Marie-Kristin von, Gulen, Burak, Stahl, Matthias, Pett, Christian, Hedberg, Christian, Lang, Kathrin, Schneider, Sabine, Itzen, Aymelt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815794/
https://www.ncbi.nlm.nih.gov/pubmed/33469029
http://dx.doi.org/10.1038/s41467-020-20702-2