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The program of renal fibrogenesis is controlled by microRNAs regulating oxidative metabolism

Excessive accumulation of extracellular matrix (ECM) is the hallmark of fibrotic diseases. In the kidney, it is the final common pathway of prevalent diseases, leading to chronic renal failure. While cytokines such as TGF-β play a fundamental role in myofibroblast transformation, recent work has sho...

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Detalles Bibliográficos
Autores principales: Miguel, Verónica, Ramos, Ricardo, García-Bermejo, Laura, Rodríguez-Puyol, Diego, Lamas, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815809/
https://www.ncbi.nlm.nih.gov/pubmed/33465566
http://dx.doi.org/10.1016/j.redox.2020.101851