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TNFα promotes oral cancer growth, pain, and Schwann cell activation

Oral cancer is very painful and impairs a patient’s ability to eat, talk, and drink. Mediators secreted from oral cancer can excite and sensitize sensory neurons inducing pain. Cancer mediators can also activate Schwann cells, the peripheral glia that regulates neuronal function and repair. The cont...

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Detalles Bibliográficos
Autores principales: Salvo, Elizabeth, Tu, Nguyen H., Scheff, Nicole N., Dubeykovskaya, Zinaida A., Chavan, Shruti A., Aouizerat, Bradley E., Ye, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815837/
https://www.ncbi.nlm.nih.gov/pubmed/33469141
http://dx.doi.org/10.1038/s41598-021-81500-4