Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration

In self-renewing somatic tissue such as skin epidermis, terminal differentiation genes must be suppressed in progenitors to sustain regenerative capacity. Here we show that hundreds of intronic polyadenylation (IpA) sites are differentially used during keratinocyte differentiation, which is accompan...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xin, Lloyd, Sarah M., Kweon, Junghun, Gamalong, Giovanni M., Bao, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815847/
https://www.ncbi.nlm.nih.gov/pubmed/33469008
http://dx.doi.org/10.1038/s41467-020-20674-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815847/
https://www.ncbi.nlm.nih.gov/pubmed/33469008
http://dx.doi.org/10.1038/s41467-020-20674-3

Ejemplares similares