Cargando…
Washing with alkaline solutions in protein A purification improves physicochemical properties of monoclonal antibodies
Protein A affinity chromatography has been widely used for both laboratory scale purification and commercial manufacturing of monoclonal antibodies and Fc-fusion proteins. Protein A purification is specific and efficient. However, there still remain several issues to be addressed, such as incomplete...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815873/ https://www.ncbi.nlm.nih.gov/pubmed/33469121 http://dx.doi.org/10.1038/s41598-021-81366-6 |