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Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

Clostridioides difficile is a bacterial pathogen that causes a range of clinical disease from mild to moderate diarrhea, pseudomembranous colitis, and toxic megacolon. Typically, C. difficile infections (CDIs) occur after antibiotic treatment, which alters the gut microbiota, decreasing colonization...

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Detalles Bibliográficos
Autores principales: Fletcher, Joshua R., Pike, Colleen M., Parsons, Ruth J., Rivera, Alissa J., Foley, Matthew H., McLaren, Michael R., Montgomery, Stephanie A., Theriot, Casey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815924/
https://www.ncbi.nlm.nih.gov/pubmed/33469019
http://dx.doi.org/10.1038/s41467-020-20746-4