Development of CAR-T Cell Persistence in Adoptive Immunotherapy of Solid Tumors

Chimeric antigen receptor (CAR) T (CAR-T) cell transfer has made great success in hematological malignancies, but only shown a limited effect on solid tumors. One of the major hurdles is the poor persistence of infused cells derived from ex vivo activation/expansion and repeated antigen encounter af...

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Detalles Bibliográficos
Autores principales: Fan, Jiaqiao, Das, Jugal Kishore, Xiong, Xiaofang, Chen, Hailong, Song, Jianxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815927/
https://www.ncbi.nlm.nih.gov/pubmed/33489881
http://dx.doi.org/10.3389/fonc.2020.574860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815927/
https://www.ncbi.nlm.nih.gov/pubmed/33489881
http://dx.doi.org/10.3389/fonc.2020.574860

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