A Genetic Screen Identifies Etl4-Deficiency Capable of Stabilizing the Haploidy in Embryonic Stem Cells

Mammalian haploid embryonic stem cells (haESCs) hold great promise for functional genetic studies and forward screening. However, all established haploid cells are prone to spontaneous diploidization during long-term culture, rendering application challenging. Here, we report a genome-wide loss-of-f...

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Detalles Bibliográficos
Autores principales: Zhang, Guozhong, Li, Xiaowen, Sun, Yi, Wang, Xue, Liu, Guang, Huang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815943/
https://www.ncbi.nlm.nih.gov/pubmed/33440180
http://dx.doi.org/10.1016/j.stemcr.2020.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815943/
https://www.ncbi.nlm.nih.gov/pubmed/33440180
http://dx.doi.org/10.1016/j.stemcr.2020.11.016

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