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Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma

BACKGROUND: Patients with malignant melanoma often relapse after treatment with BRAF and/or mitogen‐activated protein kinase kinase (MEK) inhibitors (MEKi) owing to development of drug resistance. OBJECTIVES: To establish the temporal pattern of CD271 regulation during development of resistance by m...

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Detalles Bibliográficos
Autores principales: Verykiou, S., Alexander, M., Edwards, N., Plummer, R., Chaudhry, B., Lovat, P.E., Hill, D.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816093/
https://www.ncbi.nlm.nih.gov/pubmed/30339727
http://dx.doi.org/10.1111/bjd.17333