Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney

Hypomagnesaemia is a common feature of renal Na(+) wasting disorders such as Gitelman and EAST/SeSAME syndrome. These genetic defects specifically affect Na(+) reabsorption in the distal convoluted tubule, where Mg(2+) reabsorption is tightly regulated. Apical uptake via TRPM6 Mg(2+) channels and ba...

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Detalles Bibliográficos
Autores principales: Franken, Gijs A. C., Adella, Anastasia, Bindels, René J. M., de Baaij, Jeroen H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816272/
https://www.ncbi.nlm.nih.gov/pubmed/32603001
http://dx.doi.org/10.1111/apha.13528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816272/
https://www.ncbi.nlm.nih.gov/pubmed/32603001
http://dx.doi.org/10.1111/apha.13528

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