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Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney
Hypomagnesaemia is a common feature of renal Na(+) wasting disorders such as Gitelman and EAST/SeSAME syndrome. These genetic defects specifically affect Na(+) reabsorption in the distal convoluted tubule, where Mg(2+) reabsorption is tightly regulated. Apical uptake via TRPM6 Mg(2+) channels and ba...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816272/ https://www.ncbi.nlm.nih.gov/pubmed/32603001 http://dx.doi.org/10.1111/apha.13528 |