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MicroRNA-367-3p induces apoptosis and suppresses migration of MCF-7 cells by downregulating the expression of human choline kinase α

Choline kinase (ChK) catalyzes the first step in the CDP-choline pathway for the synthesis of phosphatidylcholine. The α isoform of this enzyme is overexpressed in various types of cancer and its inhibition or downregulation has been applied as an anticancer strategy. In spite of increasing attentio...

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Detalles Bibliográficos
Autores principales: Raikundalia, Sweta, Sa'Dom, Siti Aisyah Faten Mohamed, Few, Ling Ling, Too, Wei Cun See
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816280/
https://www.ncbi.nlm.nih.gov/pubmed/33574922
http://dx.doi.org/10.3892/ol.2021.12444