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IRF4 overexpression promotes the transdifferentiation of tregs into macrophage‐like cells to inhibit the development of colon cancer

BACKGROUND: Interferon regulatory factor 4 (IRF4) is a transcription factor from the IRF factor family that exerts regulatory functions in the immune system and oncogenesis. However, the biological role of IRF4 in colon cancer is still unclear. The aim of this study is to investigate whether IRF4 pa...

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Detalles Bibliográficos
Autores principales: Wang, Jiwei, Li, Song, Li, Honglang, Zhou, Xiaoshuang, Wen, Huabin, Lai, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816309/
https://www.ncbi.nlm.nih.gov/pubmed/33468159
http://dx.doi.org/10.1186/s12935-021-01766-6