Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii

BACKGROUND: Eukaryotes use distinct networks of biogenesis factors to synthesize, fold, monitor, traffic, and secrete proteins. During heterologous expression, saturation of any of these networks may bottleneck titer and yield. To understand the flux through various routes into the early secretory p...

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Detalles Bibliográficos
Autores principales: Alva, Troy R., Riera, Melanie, Chartron, Justin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816318/
https://www.ncbi.nlm.nih.gov/pubmed/33472617
http://dx.doi.org/10.1186/s12934-020-01489-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816318/
https://www.ncbi.nlm.nih.gov/pubmed/33472617
http://dx.doi.org/10.1186/s12934-020-01489-9

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