Cargando…
Translational landscape and protein biogenesis demands of the early secretory pathway in Komagataella phaffii
BACKGROUND: Eukaryotes use distinct networks of biogenesis factors to synthesize, fold, monitor, traffic, and secrete proteins. During heterologous expression, saturation of any of these networks may bottleneck titer and yield. To understand the flux through various routes into the early secretory p...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816318/ https://www.ncbi.nlm.nih.gov/pubmed/33472617 http://dx.doi.org/10.1186/s12934-020-01489-9 |