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No detectable alloreactive transcriptional responses under standard sample preparation conditions during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclear cells

BACKGROUND: Single-cell RNA sequencing (scRNA-seq) provides high-dimensional measurements of transcript counts in individual cells. However, high assay costs and artifacts associated with analyzing samples across multiple sequencing runs limit the study of large numbers of samples. Sample multiplexi...

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Detalles Bibliográficos
Autores principales: McGinnis, Christopher S., Siegel, David A., Xie, Guorui, Hartoularos, George, Stone, Mars, Ye, Chun J., Gartner, Zev J., Roan, Nadia R., Lee, Sulggi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816397/
https://www.ncbi.nlm.nih.gov/pubmed/33472616
http://dx.doi.org/10.1186/s12915-020-00941-x