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Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells

BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent form of liver malignancy and carries poor prognoses due to late presentation of symptoms. Treatment of late-stage HCC relies heavily on chemotherapeutics, many of which target cellular energy metabolism. A key platform for testing cand...

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Detalles Bibliográficos
Autores principales: Schmidt, Cameron A., McLaughlin, Kelsey L., Boykov, Ilya N., Mojalagbe, Rafiq, Ranganathan, Arthi, Buddo, Katherine A., Lin, Chien-Te, Fisher-Wellman, Kelsey H., Neufer, P. Darrell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816515/
https://www.ncbi.nlm.nih.gov/pubmed/33468237
http://dx.doi.org/10.1186/s40170-021-00241-0