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Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells
BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent form of liver malignancy and carries poor prognoses due to late presentation of symptoms. Treatment of late-stage HCC relies heavily on chemotherapeutics, many of which target cellular energy metabolism. A key platform for testing cand...
Autores principales: | Schmidt, Cameron A., McLaughlin, Kelsey L., Boykov, Ilya N., Mojalagbe, Rafiq, Ranganathan, Arthi, Buddo, Katherine A., Lin, Chien-Te, Fisher-Wellman, Kelsey H., Neufer, P. Darrell |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816515/ https://www.ncbi.nlm.nih.gov/pubmed/33468237 http://dx.doi.org/10.1186/s40170-021-00241-0 |
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