Biochemical features and mutations of key proteins in SARS-CoV-2 and their impacts on RNA therapeutics

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Three viral proteins, the spike protein (S) for attachment of virus to host cells, 3-chymotrypsin-like cysteine protease (M(pro)) for digestion of viral polyproteins to functional proteins, and RNA-dependent-R...

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Detalles Bibliográficos
Autores principales: Zeng, Li, Li, Dongying, Tong, Weida, Shi, Tieliu, Ning, Baitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816569/
https://www.ncbi.nlm.nih.gov/pubmed/33482149
http://dx.doi.org/10.1016/j.bcp.2021.114424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816569/
https://www.ncbi.nlm.nih.gov/pubmed/33482149
http://dx.doi.org/10.1016/j.bcp.2021.114424

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