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Biochemical features and mutations of key proteins in SARS-CoV-2 and their impacts on RNA therapeutics
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. Three viral proteins, the spike protein (S) for attachment of virus to host cells, 3-chymotrypsin-like cysteine protease (M(pro)) for digestion of viral polyproteins to functional proteins, and RNA-dependent-R...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816569/ https://www.ncbi.nlm.nih.gov/pubmed/33482149 http://dx.doi.org/10.1016/j.bcp.2021.114424 |