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Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations

Mechanisms that control nuclear membrane remodeling are essential to maintain the integrity of the nucleus but remain to be fully defined. Here, we identify a phosphatidic acid (PA)–binding capacity in the nuclear envelope (NE)–specific ESCRT, Chm7, in budding yeast. Chm7’s interaction with PA-rich...

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Detalles Bibliográficos
Autores principales: Thaller, David J., Tong, Danqing, Marklew, Christopher J., Ader, Nicholas R., Mannino, Philip J., Borah, Sapan, King, Megan C., Ciani, Barbara, Lusk, C. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816628/
https://www.ncbi.nlm.nih.gov/pubmed/33464310
http://dx.doi.org/10.1083/jcb.202004222