Cargando…

Probing the therapeutic potential of TRPC6 for Alzheimer’s disease in live neurons from patient-specific iPSCs

The induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to model and study Alzheimer’s disease (AD) under patient-specific genetic background. The lower expression of transient receptor potential canonical 6 (TRPC6) was associated with AD patients, which might be involved in AD...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Ran, Lu, Rui, Wang, Junfeng, Zeng, Shujun, Zhang, Ting, Guo, Wenke, Zhang, Xiaobing, Cheng, Qi, Yue, Chunmei, Wang, Yizheng, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816687/
https://www.ncbi.nlm.nih.gov/pubmed/32492143
http://dx.doi.org/10.1093/jmcb/mjaa027