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Probing the therapeutic potential of TRPC6 for Alzheimer’s disease in live neurons from patient-specific iPSCs
The induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to model and study Alzheimer’s disease (AD) under patient-specific genetic background. The lower expression of transient receptor potential canonical 6 (TRPC6) was associated with AD patients, which might be involved in AD...
Autores principales: | Tao, Ran, Lu, Rui, Wang, Junfeng, Zeng, Shujun, Zhang, Ting, Guo, Wenke, Zhang, Xiaobing, Cheng, Qi, Yue, Chunmei, Wang, Yizheng, Jing, Naihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816687/ https://www.ncbi.nlm.nih.gov/pubmed/32492143 http://dx.doi.org/10.1093/jmcb/mjaa027 |
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