AZD9291 Resistance Reversal Activity of a pH‐Sensitive Nanocarrier Dual‐Loaded with Chloroquine and FGFR1 Inhibitor in NSCLC

AZD9291 can effectively prolong survival of non‐small cell lung cancer (NSCLC) patients. Unfortunately, the mechanism of its acquired drug resistance is largely unknown. This study shows that autophagy and fibroblast growth factor receptor 1 signaling pathways are both activated in AZD9291 resistant...

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Detalles Bibliográficos
Autores principales: Gu, Yu, Lai, Songtao, Dong, Yang, Fu, Hao, Song, Liwei, Chen, Tianxiang, Duan, Yourong, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816715/
https://www.ncbi.nlm.nih.gov/pubmed/33511016
http://dx.doi.org/10.1002/advs.202002922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816715/
https://www.ncbi.nlm.nih.gov/pubmed/33511016
http://dx.doi.org/10.1002/advs.202002922

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