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Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals

Nanomechanical properties of amyloid fibrils and nanocrystals depend on their secondary and quaternary structure, and the geometry of intermolecular hydrogen bonds. Advanced imaging methods based on atomic force microscopy (AFM) have unravelled the morphological and mechanical heterogeneity of amylo...

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Detalles Bibliográficos
Autores principales: Adamcik, Jozef, Ruggeri, Francesco Simone, Berryman, Joshua T., Zhang, Afang, Knowles, Tuomas P. J., Mezzenga, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816722/
https://www.ncbi.nlm.nih.gov/pubmed/33511004
http://dx.doi.org/10.1002/advs.202002182