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Estrogen receptor beta signaling in CD8(+) T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

The non-overlapping functions of the two estrogen receptor subtypes, ERα (Estrogen Receptor α)and ERβ (Estrogen Receptor β), in tumor cells have been studied extensively. However, their counterparts in host cells is vastly underinterrogated. Even less is known about how ERα and ERβ activities are re...

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Detalles Bibliográficos
Autores principales: Yuan, Bin, Clark, Curtis A, Wu, Bogang, Yang, Jing, Drerup, Justin M, Li, Tianbao, Jin, Victor X, Hu, Yanfen, Curiel, Tyler J, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816924/
https://www.ncbi.nlm.nih.gov/pubmed/33462142
http://dx.doi.org/10.1136/jitc-2020-001932