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Optimal tuning of weighted kNN- and diffusion-based methods for denoising single cell genomics data

The analysis of single-cell genomics data presents several statistical challenges, and extensive efforts have been made to produce methods for the analysis of this data that impute missing values, address sampling issues and quantify and correct for noise. In spite of such efforts, no consensus on b...

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Detalles Bibliográficos
Autores principales: Tjärnberg, Andreas, Mahmood, Omar, Jackson, Christopher A., Saldi, Giuseppe-Antonio, Cho, Kyunghyun, Christiaen, Lionel A., Bonneau, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817019/
https://www.ncbi.nlm.nih.gov/pubmed/33411784
http://dx.doi.org/10.1371/journal.pcbi.1008569